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ScienceDaily: Top Health News

ScienceDaily: Top Health News


Promising treatment to slow kidney disease doesn't prove out in clinical trial

Posted: 27 Jun 2020 08:24 AM PDT

Progression of kidney disease in type 1 diabetes is correlated with increased amounts of uric acid. A drug that reduces uric acid levels was tested in a multi-institution randomized clinical trial. Though the study did not show the desired clinical benefit, it did provide a very clear answer to an important scientific question.

Repeated head impacts associated with later-life depression symptoms, worse cognitive function

Posted: 26 Jun 2020 01:11 PM PDT

In the largest study of its kind, an association has been found in living patients exposed to repetitive head impacts and difficulties with cognitive functioning and depression years or decades later.

New study examines recursive thinking

Posted: 26 Jun 2020 11:14 AM PDT

A multi-institutional research team found the cognitive ability to represent recursive sequences occurs in humans and non-human primates across age, education, culture and species.

Researchers destroy cancer cells with ultrasound treatment

Posted: 26 Jun 2020 11:14 AM PDT

An international research team has developed a noninvasive technology platform for gene delivery into breast cancer cells. The technique combines ultrasound with tumor-targeted microbubbles.

Designer peptides show potential for blocking viruses, encourage future study

Posted: 26 Jun 2020 09:50 AM PDT

Chemically engineered peptides could prove valuable in the battle against some of the most persistent human health challenges. New findings demonstrate how researchers can engineer peptides capable of selectively and specifically binding to polysialic acid (PSA) -- a carbohydrate that is present in many human cells and plays a key role in various physiological and pathological processes, including neurological development and disease progression.

New protein complex gets chromosomes sorted

Posted: 26 Jun 2020 08:48 AM PDT

Researchers have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division. The complex, NWC, is made up of three proteins: NOL11, WDR43, and Cirhin. In the absence of NWC, Aurora B did not accumulate at centromeres, and chromosome movement and alignment were impaired. Together, these results show that NWC is required for faithful chromosome segregation.

Computational model decodes speech by predicting it

Posted: 26 Jun 2020 08:48 AM PDT

UNIGE scientists developed a neuro-computer model which helps explain how the brain identifies syllables in natural speech. The model uses the equivalent of neuronal oscillations produced by brain activity to process the continuous sound flow of connected speech. The model functions according to a theory known as predictive coding, whereby the brain optimizes perception by constantly trying to predict the sensory signals based on candidate hypotheses (syllables in this model).

From the lab, the first cartilage-mimicking gel that's strong enough for knees

Posted: 26 Jun 2020 08:47 AM PDT

The thin, slippery layer of cartilage between the bones in the knee is magical stuff: strong enough to withstand a person's weight, but soft and supple enough to cushion the joint against impact, over decades of repeat use. That combination of soft-yet-strong has been hard to reproduce in the lab. But now, researchers say they've created an experimental gel that's the first to match the strength and durability of the real thing.

Marine training may take more mental than physical grit

Posted: 26 Jun 2020 06:27 AM PDT

A new study identifies psychological measures that may predict who is more likely to complete - or quit - a demanding marine training course.

Comparing 13 different CRISPR-Cas9 DNA scissors

Posted: 26 Jun 2020 06:27 AM PDT

Scientists have achieved the most extensive high-throughput analysis of CRISPR-Cas9 activities. The team developed deep-learning-based computational models that predict the activities of SpCas9 variants for different DNA sequences. This study represents a useful guide for selecting the most appropriate SpCas9 variant.

Long-term use of muscle relaxants has skyrocketed since 2005

Posted: 26 Jun 2020 06:27 AM PDT

Researchers found the drugs were prescribed disproportionately to older adults, often concurrently with opioids, despite warnings against this dangerous combination.

Critical new allergy pathway

Posted: 25 Jun 2020 01:22 PM PDT

Researchers have identified the sequence of molecular events by which tiny, tick-like creatures called house dust mites trigger asthma and allergic rhinitis.

Microbiome of anticancer compound-producing marine invertebrate

Posted: 25 Jun 2020 01:22 PM PDT

Could the cure for melanoma - the most dangerous type of skin cancer -- be a compound derived from a marine invertebrate that lives at the bottom of the ocean? A group of scientists think so, and are looking to the microbiome of an Antarctic ascidian called Synoicum adareanum to better understand the possibilities for development of a melanoma-specific drug.

Scientists devise new 'bar code' method to identify critical cell types in the brain

Posted: 25 Jun 2020 01:22 PM PDT

A discovery could pave the way for future studies aimed at developing solutions to ALS and other vexing neuromuscular diseases.

Superbug impact on the gut

Posted: 25 Jun 2020 07:25 AM PDT

Researchers have discovered that the devastating bacterial superbug Clostridioides difficile hijacks the human wound healing system in order to cause serious and persistent disease, opening up the development of new therapies to treat the disease.

The tug-of-war at the heart of cellular symmetry

Posted: 25 Jun 2020 07:25 AM PDT

Researchers develop an artificial cell that brings to light the dynamics that govern each cell's internal symmetry. Two coexisting actomyosin networks with opposing functions exists in cells: a ring-like centripetal actomyosin that pushes toward the center, and radially-formed bulk actomyosin bridges that pull to the edges.

A vital game of hide-and-seek elucidated by novel single-molecule microscopy

Posted: 24 Jun 2020 09:04 AM PDT

Life depends on an intricate game of hide-and-seek taking place inside the cell. New research sheds light on the mechanisms with which DNA-binding proteins search the genome for their specific binding sites.

Towards an AI diagnosis like the doctor's

Posted: 24 Jun 2020 09:04 AM PDT

Artificial intelligence is an important innovation in diagnostics, but the way these systems work is opaque. In a new article, researchers describe how they can make the AI show how it's working, as well as let it diagnose more like a doctor, thus making AI more relevant to clinical practice.